Overview

Freestone provides outsourced business and corporate development along with commercial insight in the life science industry. Our focus is on delivering integrated solutions to address needs associated with building, growing and investing in early and emerging stage life science companies.

Engagements are geared toward increasing capacity in the creation and execution of strategies, expansion or extension of operational depth and ultimately, contributing to accelerated milestone achievement and returns. A value-centric focus is utilized to align objectives and dissolve barriers to success.

Our insight and contributions rely on an appropriate foundation of research and analysis to develop and implement business plans. Deliverables provide solutions to business challenges across a range of needs from advisory projects to interim infrastructure support.

Freestone utilizes extensive operational experience to work with organizations to enhance strategies for growth and accelerate the realization of value.

Clients

Our focus is on early and emerging companies with reach into those in growth and expansion phases of the business life cycle. Regardless of stage, a common characteristic among clients is a high level of need and recognized value of capital efficient outsourcing to drive productivity and results.

Innovation/Early Stage Companies	Emerging/Expansion Stage Companies
Inception or first phases of growth Developing or evolving business plans Research/preclinical - Phase 2 product candidates Seeking initial and/or follow on funding	Accelerating or transition phase of growth Expanding or enhancing business plans Phase 1 - prelaunch/marketed products Funded and/or seeking expansion

Freestone also works with Investors to augment internal operations of their portfolio companies to accelerate milestone achievement and secure partnerships. Once an investment has been made, enhancing and extending operational depth without taking on full time resources can be a delicate balance. Freestone provides increased business and corporate development depth as well as commercial insight in portfolio companies and does so in an on-demand fashion. Our approach aligns initiatives and fills gaps to create differentiation, reduce risk and increase the potential for positive returns.

Engagements associated with investing in life science companies also include deal flow support as an extension of the team identifying and evaluating new investment opportunities and due diligence through participation in review of investments under consideration.

Capabilities

Freestone concentrates on integrating business insight and novel science with focused execution. The alignment of clinical, regulatory and commercial perspectives results in identification, creation and realization of value. Our integrated solutions effectively recognize viable opportunities and delineate clear paths to success.

Business Strategy	Corporate Strategy	Commercial Insight
Prioritization and optimization of pipelines and portfolios Sourcing, screening, and evaluation of new opportunities Structuring and analysis of partnership alternatives Due diligence and collaborative deal execution Lead or supplement internal operations	Development of differentiated product and technology alternatives Integration of clinical, regulatory and commercial initiatives Evaluation and analysis of scenarios to generate growth opportunities Drafting of execution plans to advance operations Lead or supplement internal operations	Opportunity analysis to determine value and guide decision making Development of differentiated product profiles and business plans Market research, analysis and modeling for scenario planning Positioning, targeting, segmentation, and key message development Lead or supplement internal operations

Alliances

Freestone affiliates and advisors have tenured depth across key complementary functional areas in the life science and health care industries. Where needed, partnerships from a broad network of industry experts and professional partners are utilized to deliver solutions to the most challenging business situations.

Alliances in key complementary areas
General counsel and intellectual property   Reimbursement and managed marketing   Clinical plan design and medical documents   Regulatory strategy and promotion policies   Corporate communications and branding

Value

Freestone provides a platform of integrated solutions to deliver meaningful technology and product differentiation. Creating innovative business strategies and viable execution alternatives to realize the value of client interests is our top priority. We are dedicated to providing objectivity to support risk-adjusted decision making and drive effective implementation.

Differentiation from proof of concept to marketplace	Cross functional integration in overall business operations
Developing company and product value propositions Enhancing and implementing business strategies Building awareness and attracting interest Creating partnership and collaboration opportunities	Guiding decision making and implementation of growth strategies Overcoming business growth barriers and challenges Reducing risk associated with investment of resources Increasing positive outcomes and likelihood marketplace success

Value is added to client business through first-hand operational experience and resolve to implement initiatives and deliver results. We turn data and information into insight and solutions through the application of streamlined approaches and methodologies.

Case Studies

Private, venture backed discovery and development company focused on synthesizing novel compounds targeting metabolic disorders, inflammation and pain.	Private, specialty pharmaceutical company with a portfolio of marketed products and candidates in the fields of CNS disorders, female health and urology.
Situation: Scientific founders and investors seeking to advance business development initiatives to secure a strategic partner.	Situation: Leadership seeking strategic guidance on value drivers, key messages and partnership opportunity for pipeline product.
Approach: Retained to assume leadership of all business development and partnering activities including identification, evaluation and negotiations of transactions.	Approach: Completed primary and secondary market research with internal and external stakeholder to obtain insight. Created target product profile to analyze multiple scenarios.
Deliverables: Marketing materials including executive summary, roadshow and due diligence packages. Initiation, management and tracking of all communications with potential partners and investors. Multiple term sheets and leadership of negotiations with mid-sized and large pharmaceutical partners.	Deliverables: Business insight report with findings from market research, opportunity analyzer model to forecast market and product scenarios. Alternative business model options, go-to- market approaches and partnership scenarios to guide decision making for target product profile.
Value: Enhanced existing business strategy, provided clarity of messages and exit alternatives. Expanded business and commercial depth of management team. Created competitive interest towards completion of definitive agreement.	Value: Objective view of portfolio and life cycle management options, viable business and execution alternatives aligned with data-driven scenarios. Research and guidance provided clear direction for distinct go/no go decision making.